| 货号 | 2201/50 |
| 别名 | 1,2,3,4,5,6-Hexahydro-6-methyl-azep |
| 供应商 | Tocris |
| 生物活性 | Potent 5-HT2C agonist and partial 5-HT2A/5-HT2B agonist. Non-selective between 5-HT2 receptor subtypes (Ki values are 18, 18 and 66 nM for human recombinant 5-HT2C, 5-HT2A and 5-HT2B receptors respectively). Reduces food intake in rats following subcutaneous administration and displays anorexigenic effects in humans. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 236.74 |
| 分子式 | C13H16N2.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 15923-78-1 |
| 参考文献 | Jensenet al (2013) Design, synthesis and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT2A/5-HT2C receptor agonists with pro-cognitive properties. J.Med.Chem. 561211. McCallet al (2001) PNU-22394, a 5-HT2C receptor agonist, reduces feeding in rodents and produces weight loss in humans. Soc.Neurosci.Abstr. 27309. . |