L002 (50 MG)
货号：
5045/50 基本售价：
8615.7 元 规格：
50 mg
产品信息
概述| 货号 | 5045/50 |
| 别名 | 4-[O-[(4-Methoxyphenyl)sulfonyl]oxime]-2,6-dimethyl-2,5-cyclohexadiene-1,4-dione |
性能| 供应商 | Tocris |
| 生物活性 | p300 inhibitor (IC50 = 1.98 μM). Inhibits histone and p53 acetylation, and suppresses STAT3 activation in cell-based assays. Also suppresses tumor growth in a mouse MDA-MB-468 xenograft model. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 321.35 |
| 分子式 | C15H15NO5S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol with gentle warming |
| 参考文献 | Yanget al (2013) Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents. Mol.Cancer Ther. 12 610. PMID: 23625935. |
