A-939572
货号：
19123-50mg 基本售价：
8610.0 元 规格：
50 mg
产品信息
概述| 货号 | 19123-50mg |
| 描述 | A-939572 inhibits stearoyl-CoA desaturase 1 (IC50 = 6.3 nM), a key enzyme for lipid metabolism that is expressed in human pluripotent stem cells (hPSCs).1 This compound has been used to induce cell death of hPSCs as well as to inhibit the proliferation of human non-small cell lung carcinoma H1299 cells in vitro.1,2 |
| 别名 | SCD1 Inhibitor;Stearoyl-CoA Desaturase 1 Inhibitor; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Roongta, U.V.,Pabalan, J.G.,Wang, X., et al. Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy. Mol. Cancer Res. 9(11), 1551-1561 (2011).
2.Ben-David, U.,Gan, Q.F.,Golan-Lev, T., et al. Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen. Cell Stem Cell 12(2), 167-179 (2013).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 387.9 |
| 分子式 | C20H22ClN3O3 |
| CAS号 | 1032229-33-6 |
| 稳定性 | ≥ 2 years |
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