2-Phenyl-2-(1-piperidinyl)propane
货号：
17799-25mg 基本售价：
8582.0 元 规格：
25 mg
产品信息
概述| 货号 | 17799-25mg |
| 描述 | 2-Phenyl-2-(1-piperidinyl)propane is an analog of phencyclidine that acts as a mechanism-based inactivator of human cytochrome P450 (CYP) 2B6 (Ki = 5.6 µM; IC50 = 5.1 µM).1 It is 15-fold more selective for inhibition of CYP2B6 over CYP2D6 and 40-60-fold more selective for CYP2B6 over CYP1A2, CYP2A6, CYP2Cs, and CYP3A.1 |
| 别名 | 1-(α,α-dimethylbenzyl)-Piperidine;PPP; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Walsky, R.L. and Obach, R.S. A comparison of 2-phenyl-2-(1-piperidinyl)propane (PPP), 1,1,1"-phosphinothioylidynetrisaziridine (ThioTEPA), clopidogrel, and ticlopidine as selective inactivators of human cytochrome P450 2B6. Drug Metabolism and Disposition 35(11), 2053-2059 (2007).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 203.3 |
| 分子式 | C14H21N |
| CAS号 | 92321-29-4 |
| 稳定性 | ≥ 1 year |
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