货号 | 0722/50 |
供应商 | Tocris |
生物活性 | A pro-drug of the potent vasorelaxant nitroxyl, H-N=O, which it slowly releases in neutral solution. HNO eventually dimerizes and dehydrates to N2O, without producing NO. Also a powerful inhibitor of aldehyde dehydrogenase. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
计算分子量 | 291.71 |
分子式 | C10H10CINO5S |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 142867-52-5 |
参考文献 | Fukutoet al (1992) N,O-Diacylated-N-hydroxyarylsulfonamides: nitroxyl precursors with potent smooth muscle relaxant properties. Biochem.Biophys.Res.Commun. 187 1367. PMID: 1417812. Leeet al (1992) Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase. J.Med.Chem. 35 3648. PMID: 1433175. |