| 货号 | 2642/50 |
| 别名 | 2-[[4-(4-Fluorophenoxy)phenyl]methy |
| 供应商 | Tocris |
| 生物活性 | Broad spectrum, state-dependent blocker of voltage-gated sodium channels. Displays ~ 80-fold higher affinity for inactivated Na+ channels compared to channels in the resting state. Anticonvulsant; displays activity in rodent models of tonic/clonic and partial-complex seizures. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 273.26 |
| 分子式 | C14H12FN3O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 181144-66-1 |
| 参考文献 | Ilyinet al (2006) Pharmacology of 2-[4-(4-chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide: a potent, broad-spectrum state-dependent sodium channel blocker for treating pain states. J.Pharmacol.Exp.Ther. 318 1083. PMID: 16728593. Ilyinet al (2005) V102862 (Co 102862): a potent, broad-spectrum state-dependent blocker of mammalian voltage-gated sodium channels. Br.J.Pharmacol. 144 801. PMID: 15778702. |