Vinyl-L-NIO (hydrochloride)
货号：
80330-100mg 基本售价：
8428.0 元 规格：
100 mg
产品信息
概述| 货号 | 80330-100mg |
| 描述 | Vinyl-L-NIO is a potent, selective inhibitor of nNOS. The Ki values for inhibition of nNOS, eNOS, and iNOS by vinyl-L-NIO are 100 nM, 12 and 60 µM, respectively, as determined using initial rate measurements.1 In the presence of NADPH and O2, vinyl-L-NIO irreversibly inactivates nNOS with a kinact of 0.078 min−1 and a Ki value of 90 nM. Vinyl-L-NIO does not inactivate iNOS. eNOS requires 20-fold higher concentrations of vinyl-L-NIO to obtain 75% the rate of inactivation seen with nNOS.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Babu, B.R., and Griffith, O.W. N5-(1-Imino-3-butenyl)-L-ornithine. A neuronal isoform selective mechanism-based inactivator of nitric oxide synthase. The Journal of Biological Chemisty 273, 8882-8889 (1998).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 235.7 |
| 分子式 | C9H17N3O2 • HCl |
| CAS号 | 728944-69-2 |
| 稳定性 | ≥ 1 year |
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