5(S)-HpETE
货号：
44230-250ug 基本售价：
8400.0 元 规格：
250 ug
产品信息
概述| 货号 | 44230-250ug |
| 描述 | 5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. It is metabolized to leukotriene A4(LTA4), a key intermediate in the formation of LTs.1 5(S)-HpETE (1 µM) mediates the induction of the proto-oncogene c-fos in TNF-stimulated TA1 cells.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Shimizu, T.,Rådmark, O. and Samuelsson, B. Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid. Proceedings of the National Academy of Sciences of the United States of America 81, 689-693 (1984).
2.Haliday, E.M.,Ramesha, C.S. and Ringold, G. TNF induces c-fos via a novel pathway requiring conversion of arachidonic acid to a lipoxygenase metabolite. EMBO Journal 10, 109-115 (1991).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥98% |
| 计算分子量 | 336.5 |
| 分子式 | C20H32O4 |
| CAS号 | 71774-08-8 |
| 稳定性 | ≥ 6 months |
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