Aureothin
货号：
19463-5mg 基本售价：
8316.0 元 规格：
5 mg
产品信息
概述| 货号 | 19463-5mg |
| 描述 | Aureothin is a natural nitroaryl-substituted polyketide that exhibits antitumor, antifungal, and insecticidal activities.1,2 It is a non-competitive inhibitor of NADH:ubiquinone oxidoreductase of bovine heart, N. crassa, and E. coli(IC50s = 0.07, 0.08, and 22 nmol/mg protein, respectively).3 |
| 别名 | Antibiotic 74A;BRN 0058476;JA 2814K;Mycolutein;Strain 58 substance; |
性能| 供应商 | Cayman |
| 应用文献 |
1.He, J. and Hertweck, C. Iteration as programmed event during polyketide assembly; molecular analysis of the aureothin biosynthesis gene cluster. Chemistry & Biology 10(12), 1225-1232 (2003).
2.Shao, Z. and Zhao, H. DNA assembler: A synthetic biology tool for characterizing and engineering natural product gene clusters. Methods in Enzymology 517, 203-224 (2012).
3.Friedrich, T.,Van Heek, P.,Lief, H., et al. Two binding sites of inhibitors in NADH: Ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase. European Journal of Biochemistry 219(1-2), 691-698 (1994).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥96% |
| 计算分子量 | 397.4 |
| 分子式 | C22H23NO6 |
| CAS号 | 2825-00-5 |
| 稳定性 | ≥ 1 year |
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