16,16-dimethyl Prostaglandin A2
货号：
10280-10mg 基本售价：
8288.0 元 规格：
10 mg
产品信息
概述| 货号 | 10280-10mg |
| 描述 | 16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4 µg/ml.1 Daily infusion of 10 µg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%.2 Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time.3 |
| 别名 | 16,16-dimethyl PGA2; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Santoro, M.G.,Benedetto, A.,Carruba, G., et al. Prostaglandin A compounds as antiviral agents. Science 209, 1032-1034 (1980).
2.Santoro, M.G.,Favalli, C.,Mastino, A., et al. Antiviral activity of a synthetic analog of prostaglandin A in mice infected with influenza A virus. Archives of Virology 99, 89-100 (1988).
3.Marini, S.,Palamara, A.T.,Garaci, E., et al. Growth inhibition of friend erythroleukaemia cell tumours in vivo by a synthetic analogue of prostaglandin A: An action independent of natural killer-activity. British Journal of Cancer 61, 394-399 (1990).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 362.5 |
| 分子式 | C22H34O4 |
| CAS号 | 41691-92-3 |
| 稳定性 | ≥ 1 year |
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