4-hydroxy Nonenal-d3
货号:
332101-1mg 基本售价:
8232.0 元 规格:
1 mg
产品信息
概述货号 | 332101-1mg |
描述 | 4-hydroxy Nonenal-d3(4-HNF-d3) contains three deuterium atoms at the terminal methyl position. It is intended for use as an internal standard for the quantification of 4-HNE by GC- or LC-mass spectrometry. 4-HNE is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid.1,2 4-HNE is widely used as a marker of lipid peroxidation.2 It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity.1,2,3 4-HNE inhibits pro-oxidant-induced Ca2+ release from mitochondria at 10-50 µM.2 |
别名 | 4-HNE-d3; |
性能供应商 | Cayman |
应用文献 |
1.Pryor, W.A. and Porter, N.A. Suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids. Free Radical Biology & Medicine 8, 541-543 (1990). 2.Esterbauer, H.,Schaur, R.J. and Zoliner, H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde, and related aldehydes. Free Radical Biology & Medicine 11, 81-128 (1991). 3.Sodum, R.S. and Chung, F.L. 1,N2-ethenodeoxyguanosine as a potential marker for DNA adduct formation by trans-4-hydroxy-2-nonenal. Cancer Research 48, 320-323 (1988).
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运输条件 | Dry ice in continental US; may vary elsewhere |
存放说明 | -80 |
纯度 | ≥99% deuterated forms (d1-d3) |
计算分子量 | 159.2 |
分子式 | C9H13D3O2 |
CAS号 | 148706-06-3 |
稳定性 | ≥ 6 months |
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