Taurochenodeoxycholic Acid (sodium salt)
货号：
20275-1g 基本售价：
8232.0 元 规格：
1 g
产品信息
概述| 货号 | 20275-1g |
| 描述 | Taurochenodeoxycholic acid (TCDCA) is a taurine-conjugated primary bile acid derived from chenodeoxycholic acid (CDCA; Item No. 10011286) in the liver and is one of the major bile acids in bile.1 Bile acids are major products of cholesterol metabolism and are essential for solubilization and transport of cholesterol and other dietary lipids.1 During an oral lipid tolerance test in human subjects, the levels of TCDCA rise approximately 5-fold in serum within two hours and begin to decrease within four hours.2 Serum levels of TCDCA, along with several other bile acids, are significantly increased in patients with liver cirrhosis and may serve as a marker of disease progression.3 |
| 别名 | NSC 681055;Taurochenodeoxycholate;TCDCA; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Hoffman, A.F. The continuing importance of bile acids in liver and intestinal disease. Arch. Intern. Med. 159(22), 2647-2658 (1999).
2.Schmid, A.,Neumann, H.,Karrasch, T., et al. Bile acid metabolome after an oral lipid tolerance test by liquid chromatography-tandem mass spectrometry (LC-MS/MS). PLoS One 11(2), e0148869 (2016).
3.Wang, X.,Xie, G.,Zhao, A., et al. Serum bile acids are associated with pathological progression of hepatitis B-induced cirrhosis. J. Proteome Res. 15(4), 1126-1134 (2016).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 521.7 |
| 分子式 | C26H44NO6S • Na |
| CAS号 | 6009-98-9 |
| 稳定性 | ≥ 2 years |
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