Epirubicin (hydrochloride)
货号：
12091-100mg 基本售价：
8232.0 元 规格：
100 mg
产品信息
概述| 货号 | 12091-100mg |
| 描述 | Epirubicin is a stereoisomer of the antitumor anthracycline doxorubicin (Item No. 15007) that undergoes β-glucuronidation, which partially detoxifies the dose-limiting side effects that are present with doxorubicin.1 Compared to doxorubicin, epirubicin is equally cytotoxic to HeLa cells (ID50s = 9 μM).1 When used either alone or in combination therapies, epirubicin has been shown to demonstrate high rates of complete or partial remission in various cancers including advanced ovary, lymphomas, breast, pancreas, gastric, hepatocellular carcinoma, head and neck tumors, and colorectal.1,2 |
| 别名 | 4’-Epidoxorubicin; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Arcamone, F. Properties of antitumor anthracyclines and new developments in their application: Cain memorial award lecture. Cancer Research 45, 5995-5999 (1985).
2.Yao, X.,Hosenpud, J.,Chitambar, C.R., et al. A phase II study of concurrent docetaxel, epirubicin and cyclophospha-mide as a neoadjuvant chemotherapy regimen in patients with locally advanced breast cancer. Journal of Cancer 3, 145-151 (2012).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 580 |
| 分子式 | C27H29NO11 • HCl |
| CAS号 | 56390-09-1 |
| 稳定性 | ≥ 2 years |
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