2-Thiouridine
货号：
21011-500mg 基本售价：
8190.0 元 规格：
500 mg
产品信息
概述| 货号 | 21011-500mg |
| 描述 | 2-Thiouridine (s2U) is a modified nucleobase found in tRNAs that is known to stabilize U:A pairs and modestly destabilize U:G wobble pairs.1,2,3 Modified nucleobases, including 2-thiouridine, are used to study nucleic acid structure and function as well as to engineer novel RNA-based biomolecules. |
| 别名 | 1-β-D-ribofuranosyl-2-thiouracil;s2U; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Heuberger, B.D.,Pal, A.,Del Frate, F., et al. Replacing uridine with 2-thiouridine enhances the rate and fidelity of nonenzymatic RNA primer extension. J. Am. Chem. Soc. 137(7), 2769-2775 (2015).
2.Kumar, R.K. and Davis, D.R. Synthesis and studies on the effect of 2-thiouridine and 4-thiouridine on sugar conformation and RNA duplex stability. Nucleic Acids Res. 25(6), 1272-1280 (1997).
3.Larsen, A.T.,Fahrenbach, A.C.,Sheng, J., et al. Thermodynamic insights into 2-thiouridine-enhanced RNA hybridization. Nucleic Acids Res. 43(16), 7675-7687 (2015).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 260.3 |
| 分子式 | C9H12N2O5S |
| CAS号 | 20235-78-3 |
| 稳定性 | ≥ 2 years |
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