Psoralidin
货号:
15119-100mg 基本售价:
8190.0 元 规格:
100 mg
产品信息
概述货号 | 15119-100mg |
描述 | Psoralidin is a furanocoumarin isolated from the seeds of P. corylifolia, a medicinal plant found in southeastern Asia, that has been shown to induce cytotoxicity against various cancer cells.1 Through TNF-related apoptosis-inducing ligand-mediated events, psoralidin at 50 μM can induce the death of HeLa cancer cells.2 It also can induce apoptosis of androgen-dependent (LNCaP, C4-2B) and androgen-independent (DU-145, PC-3) prostate cancer cells and inhibit the growth of PC-3 xenograft tumors in nude mice.3 |
性能供应商 | Cayman |
应用文献 |
1.Pahari, P. and Rohr, J. Total synthesis of psoralidin, an anticancer natural product. The Journal of Organic Chemistry 74(7), 2750-2754 (2009). 2.Bronikowska, J.,Szliszka, E.,Jaworska, D., et al. The coumarin psoralidin enhances anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Molecules 17(6), 6449-6464 (2012). 3.Kumar, R.,Srinivasan, S.,Pahari, P., et al. Activating SAPK-mediated cell death and inhibiting EGFR signaling: A promising therapeutic strategy for prostate cancer. Molecular Cancer Therapeutics 9(9), 2488-2496 (2010).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 336.3 |
分子式 | C20H16O5 |
CAS号 | 18642-23-4 |
稳定性 | ≥ 2 years |
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