AZ PFKFB3 67 ( )
货号：
5742/50 基本售价：
8110.0 元 规格：
50 mg
产品信息
概述| 货号 | 5742/50 |
| 别名 | (2S)-N-[4-[[3-Cyano-1-[(3,5-dimethyl-4-isoxazolyl)methyl]-1H-indol-5-yl]oxy]phenyl]-2-pyrrolidinecarboxamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective PFKFB3 inhibitor (IC50 values are 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 455.51 |
| 分子式 | C26H25N5O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Boydet al (2015) Structure-based design of potent and selective inhibitors of the metabolic kinase PFKFB3. J.Med.Chem. 58 3611. PMID: 25849762. |
