ZINC12613047
货号：
16975-5mg 基本售价：
8050.0 元 规格：
5 mg
产品信息
概述| 货号 | 16975-5mg |
| 描述 | ZINC12613047 is a selective butyrylcholinesterase (BChE) inhibitor with an IC50 value of 21 nM for human BChE versus an IC50 value of 102.1 µM for mouse AChE.1 At 10 µM, it has been shown to inhibit Aβ1-42 self-induced aggregation by 61.7% and to protect human neuronal SH-SY5Y cells from Aβ1-42 peptide toxicity.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Brus, B.,Kosak, U.,Turk, S., et al. Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor. Journal of Medicinal Chemistry 57(19), 8167-8179 (2014).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 442.6 |
| 分子式 | C29H34N2O2 |
| CAS号 | 1069521-64-7 |
| 稳定性 | ≥ 2 years |
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