AMG-47a
货号：
2825-25 基本售价：
8004.5 元 规格：
25mg
产品信息
概述| 货号 | 2825-25 |
| 描述 | AMG-47a is a potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED₅₀ = 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice. In several other in vitro assays, AMG-47 displays subnanomolar inhibition against Lck, and low (<10 nM) inhibition against other hard to inhibit kinases such as KDR and SRC and MAPK α (p38α). In addition, at slightly higher doses but well under 10 µM, AMG-47 effectively inhibits the JNK family of kinases including TYK2 at ~ 1.2 µM. |
性能| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 外观 | Beige solid |
