| 货号 | 3518/50 |
| 别名 | 2-[2-(4-Bromophenyl)-2-oxoethyl]-1- |
| 供应商 | Tocris |
| 生物活性 | Partial agonist of α7 nAChR. Improves mnemonic function in aged mice for the treatment of aging-related memory disturbances. Displays more efficient memory-enhancing effects than memantine (Cat. No. 0773) in Alzheimer's disease mouse models. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 418.07 |
| 分子式 | C14H13BrINO |
| 可溶性/溶解性 | Soluble to 10 mM in water with gentle warming and to 100 mM in DMSO |
| CAS号 | 304679-75-2 |
| 参考文献 | Beracocheaet al (2008) Improvement of contextual memory by S 24795 in aged mice: comparison with memantine. Psychopharmacology 196 555. PMID: 18034231. Lagostenaet al (2008) The partial α7 nicotine acetylcholine receptor agonist S 24795 enhances long-term potentiation at CA3-CA1 synapses in the adult mouse hippocampus. Neuropharmacology 54 676. PMID: 18187166. Marighettoet al (2008) Comparative effects of the α7 nicotinic partial agonist, S 24795, and the cholinesterase inhibitor, donepezil, against aging-related deficits in declarative and working memory in mice. Psychopharmacology. 197 499. PMID: 18265960. |