RN 1747 (50 MG)
货号：
3745/50 基本售价：
7961.3 元 规格：
50 mg
产品信息
概述| 货号 | 3745/50 |
| 别名 | 1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine |
性能| 供应商 | Tocris |
| 生物活性 | Selective TRPV4 agonist (EC50 values are 0.77, 4.0 and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively). Displays selectivity over other TRP channels (EC50 values are 0.77, >30, >30 and >100 μM for TRPV4, TRPM8, TRPV3 and TRPV1 receptors respectively). Also antagonizes TRPM8 at relevant concentrations (IC50 = 4 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 计算分子量 | 395.87 |
| 分子式 | C17H18CIN3O4S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 102448-59-6 |
| 参考文献 | Vincentet al (2009) Identification and characterization of novel TRPV4 modulators. Biochem.Biophys.Res.Comms. 389490. |
