| 货号 | 1053/50 |
| 别名 | (E)-N-Methyl-4-(3-pyridinyl)-3-bute |
| 供应商 | Tocris |
| 生物活性 | A neuronal nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki values are 26 and 36000 nM for α4β2 and α7 receptors respectively). Active in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 252.27 |
| 分子式 | C10H14N2.C4H4O4 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 183288-99-5 |
| 参考文献 | Damajet al (1999) Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist. J.Pharmacol.Exp.Ther. 291 390. PMID: 10490929. Bencherifet al (1996) RJR-2403: a nicotinic agonist with CNS selectivity I. In vitro characterization. J.Pharmacol.Exp.Ther. 279 1413. PMID: 8968366. Lippielloet al (1996) RJR-2403: a nicotinic agonist with CNS selectivity II. In vivo characterization. J.Pharmacol.Exp.Ther. 279 1422. PMID: 8968367. |