| 货号 | 2390/50 |
| 别名 | 6-Methoxy-N-(4-methoxyphenyl)-4-qui |
| 供应商 | Tocris |
| 生物活性 | Selective mGlu1 receptor antagonist (IC50 values are 143 nM and > 10 μM for mGlu1 and mGlu5 receptors respectively). Reduces hyperalgesic behavior induced by formalin in both mouse and rat with ED50 values of 28 and 16.3 mg/kg respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 317.77 |
| 分子式 | C16H15N3O2.HCl |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| CAS号 | 338738-57-1 |
| 参考文献 | Bertorelliet al (2005) Selective blockade of metabotropic glutamate subtype mGluR1 receptors induce anti-nociceptive effects. Neuropharmacology 49 (Suppl. 1) 231. Shannonet al (2005) Anticonvulsant effects of LY456236, a selective mGlu1 receptor antagonist. Neuropharmacology 49 (Suppl. 1) 188. PMID: 16011839. |