C16 (50 MG)
货号：
5382/50 基本售价：
7961.3 元 规格：
50 mg
产品信息
概述| 货号 | 5382/50 |
| 别名 | 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one |
性能| 供应商 | Tocris |
| 生物活性 | PKR inhibitor (IC50 = 210 nM). Rescues PKR-dependent translation block in vitro. Decreases Aβ42-induced inflammatory cytokine release and apoptosis in neuronal cultures. Prevents neuroinflammation and neuronal loss in an acute excitotoxic rat model. Brain penetrant. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 268.29 |
| 分子式 | C13H8N4OS |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Tronelet al (2014) The specific PKR inhibitor C16 prevents apoptosis and IL-1 |
