13(S)-HODE methyl ester
货号：
10008875-1mg 基本售价：
7840.0 元 规格：
1 mg
产品信息
概述| 货号 | 10008875-1mg |
| 描述 | 13(S)-hydroxyoctadecadienoic acid (13(S)-HODE) is a 15-lipoxygenase metabolite of linoleic acid produced in endothelial cells, leukocytes, and tumor cells. The biological effects of 13(S)-HODE include inhibition of tumor cell adhesion to the endothelium at concentrations around 1 µM,1,2 and down regulation of IRGpIIb/IIIa receptor expression.3 13(S)-HODE methyl ester is a neutral, more lipophilic form of the free acid that can been used as an analytical standard for 13(S)-HODE. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Buchanan, M.R.,Haas, T.A.,Lagarde, M., et al. 13-Hydroxyoctadecadienoic acid is the vessel wall chemorepellant factor, LOX. The Journal of Biological Chemisty 260, 16056-16059 (1985).
2.Honn, K.V.,Nelson, K.K.,Renaud, C., et al. Fatty acid modulation of tumor cell adhesion to microvessel endothelium and experimental metastasis. Prostaglandins 44, 413-429 (1992).
3.Grossi, I.M.,Fitzgerald, L.A.,Umbarger, L.A., et al. Bidirectional control of membrane expression and/or activation of the tumor cell IRGpIIb/IIIa receptor and tumor cell adhesion by lipoxygenase products of arachidonic acid and linoleic acid. Cancer Research 49, 1029-1037 (1989).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 310.5 |
| 分子式 | C19H34O3 |
| CAS号 | 109837-85-6 |
| 稳定性 | ≥ 1 year |
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