| 货号 | 6020/50 |
| 别名 | N-[1,1'-Biphenyl]-3-yl-carbamic acid cyclohexyl ester |
| 供应商 | Tocris |
| 生物活性 | Non-competitive MAGL inhibitor. Exhibits selectivity for MAGL over FAAH, diacylglycerol lipase and COX2. Blocks 2-AG hydrolysis in rat brain slices. Enhances stress-induced analgesia in rats. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 295.38 |
| 分子式 | C19H21NO2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Hohmannet al (2005) An endocannabinoid mechanism for stress-induced analgesia. Nature. 435 1108. PMID: 15973410. Makaraet al (2005) Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus. Nat.Neurosci. 8 1139. PMID: 16116451. |