| 货号 | 1670/1 |
| 供应商 | Tocris |
| 生物活性 | Tachykinin NK1 receptor antagonist. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1386.57 |
| 分子式 | C69H91N15O16 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 129623-01-4 |
| 序列号 | XADPNKFYPLW (Modifications: X-1 = Glp, Leu-10 = spiro-g-lactam-Leu, Trp-11 = C-terminal amide) |
| 参考文献 | Guoet al (1995) Pharmacological characterisation of GR82334, a tachykinin NK1 receptor antagonist, in the isolated spinal cord of the neonatal rat. Eur.J.Pharmacol. 281 49. PMID: 8566116. Lecciet al (1992) Effect of the NK-1 receptor antagonist GR 82,334 on reflexly-induced bladder contractions. Life Sci. 51 PL277. PMID: 1335533. Haganet al (1991) A spirolactam conformationally-constrained analogue of physalaemin which is a peptidase-resistant, selective neurokinin NK-1 receptor antagonist. Br.J.Pharmacol. 102168P. |