GW-7647
货号:
9571-25 基本售价:
7157.5 元 规格:
25mg
产品信息
概述货号 | 9571-25 |
描述 | GW-7647 is a potent, selective agonist of human and murine PPARα. It activates human PPARα, PPARγ, and PPARδ with EC₅₀ values of 0.006, 1.1 and 6.2 µM, respectively, in a GAL4-PPAR binding assay. Similar EC₅₀ values of 0.001, 1.3, and 2.9 were observed with the murine receptors. Modulates oleate metabolism and mitochondrial enzyme gene expression in mature myotubules in vitro. Has lipid-lowering effects following oral administrationin vivo. Reduces NO production in macrophages; exhibits anti-inflammatory properties. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
外观 | White solid |