| 货号 | 20949-10mg |
| 描述 | β-Amyrin is a natural pentacyclic triterpenoid commonly found in plants. It is a member of the oleanane group of secondary metabolites biosynthesized from squalene in the triterpenoid pathway. β-Amyrin inhibits collagen-induced platelet aggregation (IC50 = 10.5 µM), inhibits acetylcholinesterase (IC50 = 165 µM), and has antifungal and hepatoprotective effects.1,2,3,4 Extracts of certain plants, used in herbal medicine to treat inflammation, have been shown to contain β-amyrin, suggesting that this compound contributes to anti-inflammatory actions.5 |
| 别名 | (+)-β-Amyrin;NSC 527971;Olean-12-en-3β-ol; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Ching, J.,Chua, T.K.,Chin, L.C., et al. Beta-amyrin from Ardisia elliptica Thunb. is more potent than aspirin in inhibiting collagen-induced platelet aggregation. Indian J. Exp. Biol. 48(3), 275-279 (2010). 2.Jabeen, K.,Javid, A.,Ahmad, E., et al. Antifungal compounds from Melia azedarach leaves for management of Ascochyta rabiei, the cause of chickpea blight. Nat. Prod. Res. 25(3), 264-276 (2011). 3.Oliveira, F.A.,Chaves, M.H.,Almeida, F.R., et al. Protective effect of alpha- and beta-amyrin, a triterpene mixture from Protium heptaphyllum (Aubl.) March. trunk wood resin, against acetaminophen-induced liver injury in mice. J. Ethnopharmacol. 98(1-2), 103-108 (2005). 4.Park, S.J.,Ahn, Y.J.,Oh, S.R., et al. Amyrin attenuates scopolamine-induced cognitive impairment in mice. Biol. Pharm. Bull. 37(7), 1207-1213 (2014). 5.Ferraz-Filha, Z.S.,de Paula Michel Araújo, M.C.,Ferrari, F.C., et al. Tabebuia roseoalba: In vivo hypouricemic and anti-inflammatory effects of its ethanolic extract and constituents. Planta Med. 82(16), 1395-1402 (2016). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 426.7 |
| 分子式 | C30H50O |
| CAS号 | 559-70-6 |
| 稳定性 | ≥ 2 years |
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