货号 | 1045/50 |
别名 | 6-Cyano-7-nitroquinoxaline-2,3-dion |
供应商 | Tocris |
生物活性 | More water soluble disodium salt of the AMPA/kainate antagonist CNQX (Cat. No. 0190). Also available as part of the Kainate Receptor Tocriset™. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 276.12 |
分子式 | C9H2N4O4Na2 |
可溶性/溶解性 | Soluble to 20 mM in water |
CAS号 | 115066-14-3 |
参考文献 | Kinget al (1992) Antagonism of synaptic potentials in ventral horn neurones by 6-cyano-7-nitroquinoxaline-2,3-dione: a study in the rat spinal cord in vitro. Br.J.Pharmacol. 107 375. PMID: 1358390. Longet al (1990) Effect of 6-cyano-2,3-dihydroxy-7-nitro-quinoxaline (CNQX) on dorsal root-, NMDA-, kainate and quisqualate-mediated depolarization of rat motoneurones in vitro. Br.J.Pharmacol. 100 850. PMID: 1976402. Watkinset al (1990) Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. TiPS 11 25. PMID: 2155495. Honoreet al (1988) Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science 241 701. PMID: 2899909. |