| 货号 | 0512/50 |
| 别名 | 4-(N,N-Dimethylamino)butylisothiour |
| 供应商 | Tocris |
| 生物活性 | Homolog of dimaprit (Cat. No. 0506); strong inhibitor of histamine N-methyltransferase. Exhibits no histamine agonist activity. |
| 运输条件 | Ambient |
| 存放说明 | Ambient |
| 计算分子量 | 248.21 |
| 分子式 | C7H17N3S.2HCl |
| 可溶性/溶解性 | Soluble to 75 mM in DMSO |
| CAS号 | 68643-23-2 |
| 参考文献 | Aielloet al (1997) Effects of two histamine-N-methyltransferase inhibitors, SKF 91488 and BW 301U, in rodent antinociception. Naunyn Schmiedebergs Arch.Pharmacol. 355 354. PMID: 9089666. Ohuriet al (1992) Histamine N-methyl transferase controls the contractile response of guinea pig trachea to histamine. J.Pharmacol.Exp.Ther. 261 1268. PMID: 1534842. Beaven and Shaff (1979) New inhibitors of histamine N-methyl-transferase. Biochem.Pharmacol. 28 183. PMID: 34400. Beaven and Shaff (1979) Inhibition of histamine methylation in vivo by the dimaprit analog SKF compound 91488. Agents Actions 9 455. PMID: 161853. |