| 货号 | 4050/50 |
| 别名 | 9H-Purine-6,8-diamine |
| 供应商 | Tocris |
| 生物活性 | Adenine receptor agonist (Ki = 0.0341 μM in HEK293 cells expressing an adenine binding site). Displays 190-fold increased potency at the human binding site over the rat adenine receptor (rAde1R) (Ki = 6.51 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 150.14 |
| 分子式 | C5H6N6 |
| 可溶性/溶解性 | Soluble to 100 mM in 2eq.HCl and to 50 mM in DMSO |
| 参考文献 | Borrmannet al (2009) Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family. J.Med.Chem. 52 5974. PMID: 19731917. Benderet al (2002) Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule. Proc.Natl.Acad.Sci. 998573. |