货号 | 2295/10 |
别名 | (5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3R |
供应商 | Tocris |
生物活性 | Water-soluble prostaglandin F2α(PGF2α) analog; acts as a potent FP receptor agonist (EC50 = 0.84 nM). Potently inhibits differentiation of adipocyte precursor cells. Luteolytic agent in vivo. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 446.9 |
分子式 | C22H28ClNaO6 |
可溶性/溶解性 | Soluble to 20 mM in water |
CAS号 | 55028-72-3 |
参考文献 | Serrero and Lepak (2002) Prostaglandin F2α receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined medium. Biochem.Biophys.Res.Comm. 233200. Griffinet al (1998) Pharmacological characterization of an FP prostaglandin receptor on rat vascular smooth muscle cells (A7r5) coupled to phosphoinositide turnover and intracellular calcium mobilization. J.Pharmacol.Exp.Ther. 286 411. PMID: 9655886. Dukeset al (1974) Potent luteolytic agents related to prostaglandin F2α. Nature 250 330. PMID: 4853720. |