| 货号 | 3658/50 |
| 别名 | P-(4-Methoxyphenyl)-P-4-morpholinyl |
| 供应商 | Tocris |
| 生物活性 | Slow-releasing H2S donor. Exhibits vasodilator and antihypertensive activity. Activity causes slow dilation of blood vessels in vitroandin vivo; does not influence vascular smooth muscle cell viability in culture. Water-soluble. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 376.47 |
| 分子式 | C11H16NO2PS2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Liuet al (2013) Hydrogen sulfide donor, GYY4137, exhibits anti-atherosclerotic activity in high fat fed apolipoprotein E-/- mice. Br.J.Pharmacol. [Epub ahead of print]. PMID: 23713790. Leeet al (2011) The slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitroandin vivo. PLoS One 6 e21077. PMID: 21701688. Whitemanet al (2010) The effect of hydrogen sulfide donors on lipopolysaccaride-induced formation of inflammatory mediators in macrophages. Antioxid.Redox.Signal. 12 1147. PMID: 19769459. Liet al (2008) Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137). Circulation 117 2351. PMID: 18443240. |