Glucagon Receptor Antagonist I
货号：
21223-5mg 基本售价：
5012.0 元 规格：
5 mg
产品信息
概述| 货号 | 21223-5mg |
| 描述 | Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM).1 It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver.1 Glucagon receptor antagonist I, at 50 mg/kg, reduces the increase in glucose levels observed after intraperitoneal administration of glucagon in humanized mice.1 Glucagon receptor antagonist inactive control (Item No. 21188) does not prevent glucagon-mediated actions.1 |
| 别名 | GCGR Antagonist I; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Qureshi, S.A.,Candelore, M.R.,Xie, D., et al. A novel glucagon receptor antagonist inhibits glucagon-mediated biological effects. Diabetes 53(12), 3267-3273 (2004).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥99% |
| 计算分子量 | 346.5 |
| 分子式 | C20H30N2OS |
| CAS号 | 438618-32-7 |
| 稳定性 | ≥ 1 year |
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