| 货号 | 2645-5 |
| 描述 | LGK-974 is a potent and specific inhibitor of Porcupine (porcn), a Wnt-specific acyltransferase (IC₅₀ = ~0.4 nM). GK974 potently inhibits Wnt signaling, has strong efficacy in rodent tumor models, and is well-tolerated. In addition, head and neck cancer cell lines with loss-of-function mutations in the Notch signaling pathway have a high response rate to LGK974. |
| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 外观 | Crystalline solid |