ACY-1215
货号:
2629-25 基本售价:
4320.5 元 规格:
25mg
产品信息
概述货号 | 2629-25 |
描述 | ACY-1215 is a potent, cell-permeable and selective inhibitor of histone deacetylase 6 (HDAC6) (IC₅₀ = 5 nM). ACY-1215 is 12-, 10-, 11 and 21-fold less active against HDAC1, HDAC2, HDAC3 and HDAC8, respectively. It displays minimal activities (IC₅₀ > 1 µM) against HDAC4, HDAC5, HDAC7, HDAC9, HDAC11, Sirtuin1, and Sirtuin2. In combination with Tubastatin (Cat. No. 1724), it improves cognition in Alzheimer’s Disease (AD) transgenic mice. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20 ̊C |
外观 | White to off-white solid |