(6S)-Tetrahydrofolic Acid
货号：
18263-100mg 基本售价：
4312.0 元 规格：
100 mg
产品信息
概述| 货号 | 18263-100mg |
| 描述 | (6S)-Tetrahydrofolic acid is a diastereomer of tetrahydrofolic acid (Item No. 20526), a reduced form of folic acid that serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism.1 (6S)-Tetrahydrofolic acid is 1,000-fold more active than the (6R) form at promoting the binding of fluorodeoxyuridylate to thymidylate synthase and 600-fold more active as a growth factor of P. cerevisiae.2 (6S)-Tetrahydrofolic acid also has a low affinity and high dissociation rate for folate-binding protein.3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ragsdale, S.W. Catalysis of methyl group transfers involving tetrahydrofolate and B12. Vitamins and Hormones 79, 293-324 (2008).
2.Sato, J.K.,Newman, E.M., and Moran, R.G. Preparation of (6R)-tetrahydrofolic acid and (6R)-5-formyltetrahydrofolic acid of high stereochemical purity. Anal. Biochem. 154(2), 516-524 (1986).
3.Nygren-Babol, L.,Sternesjö, Å.,Jägerstad, M., et al. Affinity and rate constants for interactions of bovine folate-binding protein and folate derivatives determined by optical biosensor technology. Effect of stereoselectivity. J. Agric. Food. Chem. 53(13), 5473-5478 (2005).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 445.4 |
| 分子式 | C19H23N7O6 |
| CAS号 | 71963-69-4 |
| 稳定性 | ≥ 2 years |
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