SAR 216471 hydrochloride ( )
货号：
5650/10 基本售价：
4302.9 元 规格：
10 mg
产品信息
概述| 货号 | 5650/10 |
| 别名 | 5-Chloro-N-[6-[5-methyl-4-(1-oxobutyl)-1H-pyrazol-1-yl]-3-pyridazinyl]-1-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-1H-indole-3-carboxamide hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Potent P2Y12 antagonist (IC50 = 17 nM). Displays antiplatelet and antithrombotic activity in vivo. Orally available. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 599.51 |
| 分子式 | C28H31ClN8O3 |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO with gentle warming |
| 参考文献 | Boldronet al(2014)N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist. J.Med.Chem. 57 7293. PMID: 25075638. |
