货号 | 2697/1 |
别名 | Galanin(1-13)-Gln14-bradykinin(2-9)amide |
供应商 | Tocris |
生物活性 | Selective galanin GAL1 receptor agonist (Ki values are 0.23 and 5.71 nM for GAL1 and GAL2 receptors respectively). Enhances food consumption in rats following i.c.v. administration and reduces CAP-induced inflammatory pain. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 2361.68 |
分子式 | C112H161N29O28 |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
CAS号 | 860790-38-1 |
序列号 | GWTLNSAGYLLGPQPPGFSPFR (Modifications: Arg-22 = C-terminal amide) |
参考文献 | Jimenez-Andradeet al (2006) Activation of peripheral galanin receptors: differential effects on nociception. Pharmacol.Biochem.Behav. 85 273. PMID: 16996122. Mazaratiet al (2006) Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: the effects of subtype-selective agonists and the role of G-protein-mediated signaling. J.Pharmacol.Exp.Ther. 318 700. PMID: 16699066. Lundstromet al (2005) A galanin receptor subtype 1 specific agonist. Int.J.Pept.Res.Ther. 1117. |