| 货号 | 3127/1 |
| 供应商 | Tocris |
| 生物活性 | Selective vasopressin V1B receptor agonist (Ki values are 0.16, 64, 100 and 3800 nM for V1B, oxytocin, V2 and V1A receptors respectively). Displays weak antidiuretic, vasopressor and in vitro oxytocic activities. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1026.2 |
| 分子式 | C47H67N11O11S2 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in water |
| CAS号 | 42061-33-6 |
| 序列号 | XYFLNCPKG (Modifications: X = Mpr, Gly-9 = C-terminal amide, Disulfide bridge between X-1 - Cys-6) |
| 参考文献 | Penaet al (2007) Design and synthesis of the frist selective agonists for the rat vasopressin V1b receptor: based on modifications of deamino-[cys1]arginine vasopressin at positions 4 and 8. J.Med.Chem. 50 835. PMID: 17300166. Penaet al (2007) Pharmacological and physiological characterization of d[Leu4,Lys8]vasopressin, the first V1b-selective agonist for rat vasopressin/oxytocin receptors. Endocrinology 148 4136. PMID: 17495006. |