| 货号 | 1650/1 |
| 供应商 | Tocris |
| 生物活性 | Potent endogenous agonist peptide for the newly identified sensory neuron specific receptor (SNSR); isolated from bovine adrenal medulla. EC50 values are 13 and 16 nM for human SNSR3 and SNSR4 respectively. Also potent opioid agonist (IC50 = 1.3 nM in guinea pig ileum preparation). Produces opioid- and non-opioid receptor mediated antinociceptive effects in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 2839.24 |
| 分子式 | C130H184N38O31S2 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 76622-26-9 |
| 序列号 | YGGFMRRVGRPEWWMDYQKRYG |
| 参考文献 | Honget al (2004) Dual effects of intrathecal BAM22 on nociceptive responses in acute and persistent pain - potential function of a novel receptor. Br.J.Pharmacol. 141 423. PMID: 14718254. Lemboet al (2002) Proenkephalin A gene products activate a new family of sensory neuron-specific GPCRs. Nat.Neurosci. 5 201. PMID: 11850634. Simonin and Kieffer (2002) Two faces for an opioid peptide - and more receptors for pain research. Nat.Neurosci. 5 185. PMID: 11865303. Mizunoet al (1980) A new family of endogenous "big" met-enkephalins from bovine adrenal medulla: purification and structure of docosa- (BAM-22P) and eicosapeptide (BAM-20P) with very potent opiate activity. Biochem.Biophys.Res.Commun. 97 1283. PMID: 7213356. |