| 货号 | 4890/5 |
| 别名 | 5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d] |
| 供应商 | Tocris |
| 生物活性 | Selective, competitive P2Y2 receptor antagonist. Inactive against a panel of 37 other receptors at a concentration of 10 μM. Inhibits ATP-γS-induced mucin secretion in bronchial epithelial cells (IC50 = 1 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 537.59 |
| 分子式 | C28H23N7O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Kempet al (2004) Nucleotide-mediated mucin secretion from differentiated human bronchial epithelial cells. Am.J.Respir.Cell Mol.Biol. 31 446. PMID: 15231488. Meghani (2002) The design of P2Y2 antagonists for the treatment of inflammatory diseases. Abstract of papers, 224th ACS National Meeting, Boston, MA. |