3-Thiatetradecanoic Acid
货号：
90500-10mg 基本售价：
4256.0 元 规格：
10 mg
产品信息
概述| 货号 | 90500-10mg |
| 描述 | 3-Thiatetradecanoic acid (3-thia TDA) is an analog of the 14-carbon saturated fatty acid myristic acid, wherein the C-3 carbon has been replaced by sulfur in a thioether linkage. When chronically administered to rats, 3-thia TDA acts as a peroxisome inducer (PPAR ligand), increases fatty acid oxidation, and lowers plasma lipid levels.1 Incorporation of 3-thia TDA into dietary regimens at 150 and 300 mg/kg in rats induces the formation of oleic acid viaΔ9-desaturase, and dose-dependently increases Δ9-desaturase mRNA levels.2 |
| 别名 | 3-TDA; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Asiedu, D.K.,Froyland, L.,Vaagenes, H., et al. Long-term effect of tetradecylthioacetic acid: A study on plasma lipid profile and fatty acid composition and oxidation in different rat organs. Biochimica et Biophysica Acta 1300, 86-96 (1996).
2.Madsen, L.,Froyland, L.,Grav, H.J., et al. Up-regulated Δ9-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: Accumulation of a Δ9-desaturated metabolite of tetradecylthioacetic acid. Journal of Lipid Research 38, 554-563 (1997).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 246.4 |
| 分子式 | C13H26O2S |
| CAS号 | 116296-31-2 |
| 稳定性 | ≥ 2 years |
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