| 货号 | 3906/50 |
| 别名 | (+)-(3β)-3-Hydroxylup-20(29)-en-28-o |
| 供应商 | Tocris |
| 生物活性 | Natural triterpenoid that displays anti-HIV and antitumor activity. Induces the production of reactive oxygen species (ROS) and activates NF-κB. Also a GPBA receptor partial agonist (EC50 = 1.04 μM, efficacy 83%). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 计算分子量 | 456.7 |
| 分子式 | C30H48O3 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| CAS号 | 472-15-1 |
| 参考文献 | Genetet al (2010) Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes. J.Med.Chem. 53 178. PMID: 19911773. Fulda (2008) Betulinic acid for cancer treatment and prevention. Int.J.Mol.Sci. 9 1096. PMID: 19325847. Kashiwadaet al (1996) Betulinic acid and dihydrobetulinic acid derivatives as potent anti-HIV agents. J.Med.Chem. 39 1016. PMID: 8676334. |