货号 | 4419/10 |
别名 | (3aS,4R,7R,9R,10R,11R,13R,15R,15aR) |
供应商 | Tocris |
生物活性 | Macrolide antibiotic. Active against multidrug resistant respiratory tract bacterial strains. Does not have the hepatotoxic side effects associated with telithromycin. Orally active. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 824.01 |
分子式 | C44H65N5O10< |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
参考文献 | Zienteket al(2010)In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase. Drug Metab.Dispos. 38 1322. PMID: 20444863. Mageeet al (2009) Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections. J.Med.Chem. 52 7446. PMID: 19775168. |