| 货号 | 1760/10 |
| 别名 | (±)-1,2,3,3a-Tetrahydro-3a-hydroxy-6 |
| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of myosin II ATPase activity; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 292.34 |
| 分子式 | C18H16N2O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 674289-55-5 |
| 参考文献 | Walkeret al (2010) Non-muscle myosin II regulates survival threshold of pluripotent stem cells. Nat.Commun. 1 71. PMID: 20842192. Limouzeet al (2004) Specificity of blebbistatin, an inhibitor of myosin II. J.Muscle Res.Cell Motil. 25 337. PMID: 15548862. Straightet al (2003) Dissecting temporal and spatial control of cytokinesis with a myosin II inhibitor. Science 299 1743. PMID: 12637748. Straightet al (2002) Dissecting cytokinesis with small molecules. Amer.Soc.Cell Biol.Abstr. 2515. |