| 货号 | 5133/10 |
| 别名 | 6-[[3-[(1S)-2-Methoxy-1-methylethox |
| 供应商 | Tocris |
| 生物活性 | Potent glucokinase activator (EC50 = 33 nM). Significantly reduces plasma glucose levels in diabetic rats; stimulates insulin release from mouse islets of Langerhans. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 464.51 |
| 分子式 | C26H28N2O6 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Johnsonet al (2007) Glucokinase activators: molecular tools for studying the physiology of insulin-secreting cells. Biochem.Soc.Trans. 35 1208. PMID: 17956314. Coopeet al (2006) Predictive blood glucose lowering efficacy by Glucokinase activators in high fat fed female Zucker rats. Br.J.Pharmacol. 149 328. PMID: 16921397. |