| 货号 | 4494/10 |
| 别名 | (R)-2,3-bis(4-Hydroxyphenyl)-propio |
| 供应商 | Tocris |
| 生物活性 | Enantiomer of DPN (Cat. No. 1494). Displays higher affinity for estrogen receptor (ER) β over ERα(Ki values are 1.82 and 147 nM respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 239.27 |
| 分子式 | C15H13NO2 |
| 可溶性/溶解性 | Soluble to 25 mM in 1eq. NaOH and to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Carrollet al (2011) Diarylpropionitrile (DPN) enantiomers: synthesis and evaluation of estrogen receptor β-selective ligands. J.Med.Chem. 55 528. PMID: 22122563. Weiseret al (2009) Estrogen receptor-β agonist diarylpropionitrile: biological activities of R- and S-enantiomers on behavior and hormonal response to stress. Endocrinology 150 1817. PMID: 19074580. |