Swinholide A
货号：
19611-50ug 基本售价：
3766.0 元 规格：
50 ug
产品信息
概述| 货号 | 19611-50ug |
| 描述 | Swinholide A is a natural dimeric dilactone macrolide toxin that causes actin depolymerization in cells.1,2 It stabilizes actin dimers and also binds to and severs F-actin filaments.1,3 Swinholide A binds to G-actin in a 1:2 molar ratio and decreases the rate of nucleotide exchange in G-actin.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bubb, M.R.,Spector, I.,Bershadsky, A.D., et al. Swinholide A is a microfilament disrupting marine toxin that stabilizes actin dimers and severs actin filaments. The Journal of Biological Chemisty 270(8), 3463-3466 (1995).
2.Saito, S.y.,Watabem, S.,Ozaki, H., et al. Actin-depolymerizing effect of dimeric macrolides, bistheonellide A and swinholide A. Journal of Biochemistry 123(4), 571-578 (1998).
3.Terry, D.R.,Higa, T. and Bubb, M.R. Misakinolide A is a marine macrolide that caps but does not sever filamentous actin. The Journal of Biological Chemisty 272(12), 7841-7845 (1997).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥97% |
| 计算分子量 | 1389.9 |
| 分子式 | C78H132O20 |
| CAS号 | 95927-67-6 |
| 稳定性 | ≥ 2 years |
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