Diclofenac-d4
货号:
19072-1mg 基本售价:
3752.0 元 规格:
1 mg
产品信息
概述货号 | 19072-1mg |
描述 | Diclofenac-d4 contains four deuterium atoms on the benzene ring. It is intended for use as an internal standard for the quantification of diclofenac (Item No. 70680) by GC- or LC-mass spectrometry. Diclofenac is a non-selective COX inhibitor.1,2,3 It inhibits human COX-1 and -2 with IC50 values of 0.9-2.7 and 1.5-20 µM, respectively.1,2 Diclofenac inhibits ovine COX-1 and -2 with IC50 values of 60 and 220 nM, respectively.3 |
别名 | Benfofen-d4;Ecofenac-d4;Voltaren-d4; |
性能供应商 | Cayman |
应用文献 |
1.Laneuville, O.,Breuer, D.K.,DeWitt, D.L., et al. Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs. Journal of Pharmacology and Experimental Therapeutics 271, 927-934 (1994). 2.Barnett, J.,Chow, J.,Ives, D., et al. Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system. Biochimica et Biophysica Acta 1209, 130-139 (1994). 3.Johnson, J.L.,Wimsatt, J.,Buckel, S.D., et al. Purification and characterization of prostaglandin H synthase-2 from sheep placental cotyledons. Arch. Biochem. Biophys. 324, 26-34 (1995).
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运输条件 | Ambient in continental US; may vary elsewhere |
存放说明 | 22 |
纯度 | ≥99% |
计算分子量 | 300.2 |
分子式 | C14H7D4Cl2NO2 |
CAS号 | 153466-65-0 |
稳定性 | ≥ 3 years |
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